Projects
Novel enzyme engineering methodology: VersaTile Shuffling Ghent University
VersaTile Shuffling is a new and robust protein engineering technology that offers numerous previously impossible opportunities to improve the properties of proteins or to create proteins with new functions. Various fields of application ranging from industrial enzymes to antibodies, aptamers and vaccines are envisaged. During the recent months we have been able to build an extensive experimental dataset that underpins the versatility of ...
VersaTile antibodies Ghent University
The inferior quality of poorly validated antibodies supplied by the major market players often disappoint customers who purchase these antibodies as a research or diagnostic reagent. These antibodies are usually of polyclonal or monoclonal descent, and exhibit poor reproducibility because their sequences are unknown. Therefore, there is an increasing demand for validated synthetic antibodies at competitive prices. VersaTile is a modular DNA ...
VersaTile Platform: innovating modular proteins by combinatorial design Ghent University
During a preliminary process (IOF StarTT 039), the VersaTile Platform has matured into a mature technology. The platform is a comprehensive DNA assembly method aimed at protein engineering and is extremely suitable for the synthetic biology of modular proteins. A service agreement with a company has been signed. Following a positive evaluation of the project, both partners aim for further negotiations concerning a license agreement.
...Versatile Easy installable Connector incorporating new Technologies for accelerated fiber Optic network Roll outs in Europe Ghent University
VECTOR aims to develop and commercialize an innovative low-cost highly performing field installable connectivity system that will impact at a multi-milion-euro scale the capital expenditure (CAPEX) and the operation expenditure (OPEX) of telecom iber broadband networkds and that will facilitate the achievement of the European 2020 objectives for broadband connectivity.
The VECTOR connectivity system will comprise a fertude-less ...
Development of the VersaTile technique and a microdroplet assay for the ultrahigh-throughput engineering of lysins as antibacterial agents KU Leuven
The discovery and development of antibiotics have shaped modern medicine. However, our health care system is increasingly threatened by antimicrobial resistance. Despite warnings since the very beginning, overuse and misuse of antibiotics have led to the emergence and spread of antimicrobial resistance against every known antibiotic. Moreover, many pharmaceutical companies have abandoned the search and development of new antibiotics due to ...
Highly versatile real-time live cell imaging for infectious disease and inflammation research. University of Antwerp
A market-fit and scalable pipeline for VersaTile antibodies Ghent University
Antibodies are among the most versatile biologics with a wide range of applications as research reagents, diagnostics and therapeutics. All these applications require an in-depth validation for a robust performance. However, in the field of research reagents and diagnostics the end-users are confronted with recurrent shortcomings when evaluating polyclonal and monoclonal antibodies. Therefore, there is a global call for well-validated ...
ChiRoPing - Developing Versatile and Robust Perception using Sonar Systems that Ingegrate Active Sensing, Morphology and Behaviour. University of Antwerp
Directed evolution of modular proteins driven by machine learning: the VersaTile Platform 2.0 Ghent University
The VersaTile Platform 1.0 is a technology developed for the synthetic biology of modular proteins. This technology is a molecular equivalent of LEGO: first, you make a collection of LEGO building blocks (equivalent of a protein module), subsequently you can make any construction (equivalent of modular protein) with these lego building blocks in a highly efficient way and with a very high throughput (up to millions of modular protein ...