Projects
Responding proactively to Covid-19 vaccination doubts to increase the effectiveness of vaccination campaigns in Belgium. KU Leuven
A transdisciplinary approach of the question of how to respond proactively to Covid-19 vaccination doubts to increase the effectiveness of vaccination campaigns in Belgium:;
Broadening the therapeutic window of LNP-based vaccination. Flanders Institute for Biotechnology
Development of virus-specific anti-NS1 antibodies and expression system for flavivirus recombinant NS1 for use in neurotropic flavivirus diagnostic, therapeutics, and vaccination development (Flavivirus_NS1_project). University of Antwerp
An integrated systems thinking approach to enhance vaccination strategies KU Leuven
The immunization system is highly complex, consisting of multiple interrelated and interacting subsystems . At the supply side, this starts with R&D (‘Innovations’-part), manufacturing, regulatory evaluation, pricing, reimbursement, distribution, clinical adoption (all in ‘National Health Program’-part), up to final product administration (‘Service Delivery’) to make sure that the vaccine ultimately reaches the people to be vaccinated ...
Sustainable COVID-19 Vaccination for Long-term Vaccine Immunity and Effectiveness KU Leuven
Despite the rapid development of various SARS-CoV-2 vaccines, the control of the pandemic is hampered by the constant emergence of SARS-CoV-2 variants escaping vaccine-induced immunity and the waning of immunity. SOLVE will tackle these challenges by deciphering the mechanisms of induction of long-lasting immunity and evaluating new vaccine platforms. To achieve this goal, an integrated plan has been developed including six pillars: 1) ...
VacxSYS: An integrated systems thinking approach to enhance vaccination strategies Hasselt University
VacxSYS: An integrated systems thinking approach to enhance vaccination strategies KU Leuven
For many human infectious diseases, especially those caused by pathogens for which no effective treatment exists, the development, production, supply and optimal allocation of effective vaccines is of paramount importance. However, achieving an effective balance between supply and demand in vaccine supply chains is challenging. Optimal decision-making in vaccine supply chains is highly complex due to the many uncertainties involved, the ...
Assessing the fundamental properties of protective IgMs in trypanosomosis, and their mode of action in vaccination. Vrije Universiteit Brussel
lymphatics, and various tissues. They cause infections in humans, livestock, and game animals.
Trypanosomes thrive in plain sight of the immune system, by deploying multiple evolutionary
acquired evasion strategies, which aim at avoiding antibody-mediated destruction as much as
possible. Interestingly, assessing ...