Projects
The yellow fever vaccine at work: Mechanisms and platform for chronic hepatitis B and COVID-19 vaccines KU Leuven
The live-attenuated yellow fever virus (YFV) vaccine YF17D has been administered hundreds of millions of times, since its development in the 1930s. It is considered an outstanding vaccine, because of its efficacy, a consequence of its ability to activate multiple arms of the immune system upon inoculation. Anti-YFV neutralizing antibodies (nAbs) have long been considered to be sufficient and required for protection. We have challenged this ...
DNA-YFVax: A DNA-based vaccine platform for tailoring of live attenuated virus vaccines for human and veterinary use KU Leuven
Kosteneffectiviteit van 7, 10 en 13-valente pneumokokken conjugaat vaccin 2009-52_HTA. University of Antwerp
Rationeel ontwerp van een therapeutisch vaccin tegen HIV-1 gebaseerd op een nieuwe formulering van nanopartikel Institute of Tropical Medicine
Stimulation of innate immune responses targeted against acute myeloid leukemia cells after exposure to Toll-like receptor ligands, with a view to the development of a leukemia vaccin. University of Antwerp
The rational design and validation of a Salmonella Typhimurium vaccin by deletion of virulence genes for use in pigs Ghent University
In this project, extensively characterized, live, attenuated vaccinstrains of Salmonella Typhimurium are made. These strains should evoke a good protection against a Salmonella infection in pigs and be attenuated in humans, animals and the environment. In addition, the pigs vaccinated with these strains, should be serologically distinguishable from pigs infected with field strains of Salmonella in the current national Salmonella pig control ...
Development of a mucosal Chlamydia trachomatis candidate recombinant vaccin Ghent University
Development of a Chlamydia trachomatis vaccin for mucosal administration in women and evaluation of the protective immune respons of different vaccin formulations using a specific pathogen free pig model of infection.