Visualization of X4-and R5-tropic HIV-1 viruses expressing fluorescent proteins in human endometrial cells: application to tropism study Institute of Tropical Medicine University of Antwerp
Worldwide most HIV infections occur through heterosexual transmission, involving complex interactions of cell-free and cell-associated particles with cells of the female genital tract mucosa. The ability of HIV-1 to "infect" epithelial cells remains poorly understood. To address this question, replicative-competent chimeric constructs expressing fluorescent proteins and harboring the envelope of X4-or R5-tropic HIV-1 strains were used to ...