Projects
Exploring innovative model systems of virus replication to unravel virus tropism and pathogenesis. KU Leuven
Viral infections are responsible for great morbidity and mortality around the world, particularly due to lower respiratory and diarrheal diseases. In addition, emerging and re-emerging viruses pose a serious threat, which is well illustrated by the ongoing COVID-19 pandemic. Understanding the fine details of how a virus infects its host, replicates and causes disease is a fundamental step towards the conceptualization and development of ...
The impact of granulomatous skin inflammation on the tissue tropism of visceral Leishmania species. University of Antwerp
Deciphering human norovirus cell tropism and pathogenesis using zebrafish KU Leuven
Human noroviruses (HuNoVs) are the most common cause of gastroenteritis, resulting in 219000 deaths/year and a societal cost of $60 billion. The lack of robust small animal models has hindered the understanding of HuNoV biology and the development of effective therapeutics. Our team established the most simple and robust HuNoV replication model available using zebrafish larvae. We will now investigate the unknown details of HuNoV pathogenesis ...
Deciphering human norovirus cell tropism and pathogenesis using zebrafish KU Leuven
Human noroviruses (HuNoVs) are the most common cause of gastroenteritis, resulting in 219000 deaths/year and a societal cost of $60 billion. The lack of robust small animal models has hindered the understanding of HuNoV biology and the development of effective therapeutics. Our team established the most simple and robust HuNoV replication model available using zebrafish larvae. We will now investigate the unknown details of HuNoV pathogenesis ...
Unraveling the in vivo host cell tropism and virus dissemination strategies of human norovirus. KU Leuven
Human noroviruses (HuNoVs) are the most common cause of gastroenteritis, resulting in 219,000 deaths/year and a societal cost of $60 billion. The lack of robust small animal models has hindered the understanding of norovirus biology and the development of effective therapeutics. Our team has recently established the most simple and robust HuNoV replication model available to date, by using zebrafish larvae. Since zebrafish larvae are small ...
Linking genomic mutations to the enterocyte-monocyte tropism switch in the feline coronavirus pathogenesis Ghent University
New tools for diagnosis and management of febrile illness in travelers to the tropics: a cohort study Institute of Tropical Medicine
Intrigerende plant-schimmel relaties in tropisch regenwoud: evolutie van myco-heterotrofe planten. KU Leuven
Beatitudo Imperfecta: An Anthology of the Concept in Aquinas and Renaissance Thomism (c. 1550 – c. 1650) KU Leuven
Thomas Aquinas (1225–1274) famously distinguishes between perfect and imperfect happiness. Both types of happiness lie in the perfection of human nature, but perfect happiness is possible only in the afterlife through the vision of God’s essence, whereas imperfect happiness is possible even in this life, be it through intellectual virtue and the contemplative life or moral virtue and the active life. This life’s imperfect happiness is the ...