Alveolar cell response to tracheal occlusion induced stretch in murine congenital diaphragmatic hernia hypoplastic lungs KU Leuven
Fetal tracheal occlusion (TO) is a clinical therapy that has been proven to promote stretch-induced lung growth by blocking the fetal trachea and preventing the egress of lung fluid. TO is offered as a prenatal intervention for patients with severe lung hypoplasia due to congenital diaphragmatic hernia (CDH). This is a birth anomaly defect of the diaphragm that allows the abdominal contents to enter the chest during fetal life, leaving ...