Bacterial toxin-antitoxin modules as drug targets Vrije Universiteit Brussel
The genomes of bacteria and archaea contain small operons encoding a "toxin" and its corresponding neutralizing "antitoxin". These gene pairs form a so-called toxin-antitoxin (TA) module of which the physiological function is heavily debated. They are activated during episodes of stress and ectopic overexpression
of the toxin leads irreversibly to cell death. TA modules are present in almost every bacterial species including S. aureus ...
of the toxin leads irreversibly to cell death. TA modules are present in almost every bacterial species including S. aureus ...