Characterisation of Priming Mechanisms for Bone Engineering at the Cellular and Molecular Level KU Leuven
Fractures of the long bones are the most common large organ trauma worldwide. In about 5% of all cases the broken bone fails to heal, resulting in a so-called non-union defect. These can be caused by a lack of potent skeletal progenitor cells at the defect site. Currently, there is no reliable treatment strategy available for these patients. Therefore, tissue engineering (TE) represents a promising approach. However, current expansion ...