Testosterone and physical activity: mechanisms of action KU Leuven
A body of evidence supports a role for a biological substrate in the disposition to be physically active vs. sedentary. For instance, our observations in the global androgen receptor (AR) knockout mouse as well as the results from castration and replacement studies point that physical activity in male mice is regulated by androgens. Similarly, in humans, low testosterone (T) levels in hypogonadal and androgen-deprived patients have been ...