Projects
Assessment of synaptic density and mHTT aggregates in post-mortem human brain tissue of patients with Huntington's Disease. University of Antwerp
Using molecular proximity to refine synapse quantification in neuronal cultures. University of Antwerp
Non-Amyloid Pathological Brain Aging in Late Life Depression KU Leuven
Multimodal PET-MRI brain imaging of white matter pathology in late life depression KU Leuven
Functional role of Protocadherin10 in murine brain development KU Leuven
Autism Spectrum Disorders (ASDs) are a group of debilitating neurodevelopmental disorders that affect millions of patients world-wide. ASD is hypothesized to arise from a complex interplay between genetic and environmental factors that impact the structure and function of the developing brain. A potential cause of the disease pathophysiology is a disrupted excitation/inhibition balance in the central nervous system stemming from abnormal ...
Brain stimulation in the age of "light": Controlling and steering cortical cellular electrophysiology for future smart neuroprosthetics employing Optogenetics. University of Antwerp
Improving neuroplasticity and motor learning by brain stimulation techniques KU Leuven
Neuroplasticity refers to the ability of the brain to change as a result of one's experience, indicating that the brain is plastic and malleable. Synaptic plasticity is the ability of synapses to strengthen or weaken over time, in response to increases or decreases of activity. In the clinical context it determines how patients with a brain injury can recover, e. g. after stroke, in order to regain independence and to perform daily life ...
Neuro-hormonal control of hunger, nutrient tolerance and food intake : from nutrient sensing to reward sensitivity. KU Leuven
Intense signalling occurs between the gastrointestinal tract and the brain. Under normal conditions, most of these signals are not perceived. We will test the hypothesis that this “Gut-to-Brain” signalling is in fact crucial for the control of food intake. We propose that the capacity for the stomach to relax during food intake, as well as the activation of anti-nociceptive pathways during meal ingestion are crucial determinants of the volume ...