DeoxyBioCat: Unlocking Synthetic Biology of Deoxy Sugars via Redesigned Biocatalytic Cascades Ghent University
Deoxysugars are special carbohydrates lacking at least one hydroxy
group. They are important building blocks and recognition sites in
functional oligosaccharides, glycoconjugates and natural glycosides
(e.g. antibiotics), in which they often critically affect bioactivity.
Deoxygenation of common sugars typically happens at nucleotide
sugar level and is catalyzed by 4,6-dehydratases that belong to the ...