Projects
Personalized characterization of the substrate of ventricular tachycardia based on simultaneous endo- and epicardial mapping and computer modelling Ghent University
A heart beat is initiated by an electrical wave that propagates through the heart and initiates cardiac contraction Abnormal wave propagation can result in cardiac arrhythmias Arrhythmias which occur in lower chambers of the heart, ventricular tachycardia and fibrillation, can lead to cardiac arrest and sudden cardiac death Currently, there are about 350000 sudden cardiac deaths in Europe each year In many cases, these dangerous arrhythmias ...
Optimization and validation of a mouse model of atherosclerotic plaque rupture. University of Antwerp
Optimalisation and validation of a mouse model of atherosclerotic plaque rupture. University of Antwerp
Personalized characterization of the substrate of ventricular tachycardia based on simultaneous endo- and epicardial mapping and computer modelling KU Leuven
A heart beat is initiated by an electrical wave that propagates through the heart and initiates cardiac contraction. Abnormal wave propagation can result in cardiac arrhythmias. Arrhythmias which occur in lower chambers of the heart, ventricular tachycardia and fibrillation, can lead to cardiac arrest and sudden cardiac death. Currently, there are about 350.000 sudden cardiac deaths in Europe each year. In many cases, these dangerous ...
Transcatheter radiofrequency ablation as a new treatment for equine atrial arrhythmias Ghent University
Cardiac arrhythmias are common in horses and may have dramatic consequences such as collapse or sudden death. Sudden death occurs 10 times more frequently in horses compared to human athletes. Options for arrhythmia treatment are currently limited to drugs or electrical shocks with one major problem: a high recurrence rate. Transcatheter radiofrequency ablation is a minimally invasive procedure in which local heating through a thin tube in ...
Right ventricular and atrial function in nature’s ultimate athlete: the horse Ghent University
Regular exercise improves health and leads to cardiac remodeling known as the athlete’s heart.
However, emerging data suggest that exercise-related pressure and volume overload may result in
detrimental remodeling of the right ventricle (RV) or atria. This has been linked to arrhythmias and
sudden death in athletes.
In this project, the horse will be used as an animal model for exercise-induced cardiac remodeling as ...
Mitral valve prolapse and associated cardiomyopathy: impact of mitral valve prolapse subtype and genetics. University of Antwerp
Brugada syndrome research to the next level: identification of genetic modifiers. University of Antwerp
Using Zebrafish as a novel tool to Improve the Diagnosis and Outcome of Marfan Syndrome Ghent University
Marfan syndrome (MFS) is a rare genetic disease, with an estimated prevalence of 1:5,000 – 1:10,000, caused by mutations in FBN1, the gene coding for fibrillin-11. MFS is a connective tissue disorder with a spectrum of symptoms involving the ocular, skeletal, and cardiovascular system. The latter is the major source of morbidity and mortality associated with MFS, due to progressive aortic dilation leading to potential aneurysm, dissection, ...