Projects
Understanding the structure-function relationship of cereal carbohydrates with regard to beer mouthfeel quality. KU Leuven
Supramolecular structure-function relationship of naturally occurring antimicrobial peptides. Ghent University
Very little is known about the structure-function relationship of the class of antimicrobial peptides known as CLPs, short for cyclic lipodepepsipeptides. Thanks to recently developed NMR methodology within our lab, we demonstrated that self-assmebly of the CLP pseudodesmin A into larger supramolecular, pore-like structures, provides the structural basis to explain its biological activity. This proposition is further explored in our ...
Patch-clamp fluorometry platform for unravelling the structure-function relationship of the GlyR Hasselt University
Understanding the structure-function relationship of carbohydrates in beer mouthfeel KU Leuven
Exploring Raman spectroscopy for elucidating structure-function relationships in complex lipid-rich foods Ghent University
Today, several societal drivers (public health, climate change, disrupting supply chains) are pushing food producers to reformulate the fat phase in their foods towards a healthier (e.g. reduce saturated fat), local and environmental sustainable (e.g. no tropical oils) and plant-based (e.g. no milk fat) profile. A prerequisite for science-driven reformulation is a thorough understanding of the structure-function relationship from the nano-, ...
Unlocking the potential of plant proteins for structuring food by building structure-function relationships KU Leuven
A highly relevant topic in the global food system, now and in decades to come, is the shift from animal protein towards plant protein based foods. Proteins play important roles in determining food structure and texture, e.g. in gelled systems, fibrous meat products or dispersed systems such as food foams and emulsions. Most plant proteins have inferior technological functionality in such systems when compared to animal proteins. Establishing ...
Supramolecular structure-function relationships of antimicrobial peptides from the viscosin group: a combined approach via synthesis and advanced NMR structure analysis Ghent University
Antimicrobial peptides or AMPs are a potential source of new first line defense antibiotics, which often act through the formation of supramolecular assemblies inside the cell membrane, e.g. by pore formation.
In this mutlidisciplinary project a generic synthesis approach will be developed, allowing the production of analogues featuring a number of modifications in composition and stereochemistry. Using recently developed NMR ...
The ecological role & structure-activity relationship of antimicrobial linear azol(in)e-containing peptides in foodborne human pathogens KU Leuven
The obese brain: the relationship between brain structure, neurocognitive functioning and motor coordination in obese children Ghent University
This proposal will be carried out in the Motor Control research group led by Prof. M. Lenoir. In this group the main focus is on motor competence in children and adolescents (typically developing, DCD, gifted children, athletes) with about 10 ongoing PhD projects. The group is internationally recognized as one of the pioneers to focus on the mechanisms of lower motor competence in obese (OB) children and has a long-standing research ...