Stem Cell and Developmental Biology KU Leuven
research
1. Pluripotent Stem Cells and Reprogramming
2. Pluripotent Stem Cell Differentiation
3. Adult Stem Cells
4. Disease Modelling and Regenerative Therapies
research
1. Pluripotent Stem Cells and Reprogramming
2. Pluripotent Stem Cell Differentiation
3. Adult Stem Cells
4. Disease Modelling and Regenerative Therapies
We want to force a breakthrough in the cure of neuronal and neurodegenerative disorders. This requires a deep understanding of normal brain function and translation of this knowledge into a solid mechanistic understanding of disease mechanisms.
The research program of the Laboratory for Molecular Cancer Biology is devoted to the analysis of pathways governing the genesis, progression and maintenance of cancer.Our current research efforts follow from our recent studies on the p53 tumor suppressor. p53 is a transcription factor that functions as a central component of most cellular stress responses. The outcome of p53-mediated surveillance is closely dependent on the type of stress ...
Our team wants to find ways to generate new insulin-producing, glucose-regulated "beta" cells that can be used for transplantation in diabetes patients and ways to regenerate beta cells in the pancreas. We study rodent experimental models as well as human cells. The first aim is based on tissue engineering starting from: 1. Exocrine pancreatic cells: reprogramming of adult exocrine cells to endocrine cells, or transdifferentiation in culture. ...
Our research team studies spermatogenesis with a special focus on spermatogonial stem cells. Our current aim is to develop strategies in order to prevent infertility after gonadotoxic treatments. Fertility can be preserved by either limiting the loss of gametes and their precursors or by storing gametes and/or their precursors. Gonadotoxicity is an important side effect of cancer treatments. While adult men can bank their spermatozoa prior to ...
The faculty departement Immunology and Microbiology (IMMI) groups the teaching on Immunology, Hematology and Microbiology of the faculty of Medicine.Most of the teaching staffmembers also have appointments in clinical departements of the university hospital (see AZ VUB). IMMI harbours several research groups clustered around two main topics: A/ Biology and treatment of haematological diseases. This activity is spread over the departments of ...
The In Vitro Toxicology and Dermato-cosmetology (IVTD) research group of the Vrije Universiteit Brussel (VUB) constitutes a hub for many promising R&D projects within a broad scientific scope. They all share one common goal, namely an improvement of human health and safety. We achieve this by:
Faculty of Medicine and Pharmacy
The Research Department of Embryology and Genetics (EMGE) is linked to the Centres for Medical Genetics and Reproductive Medicine and the Department of Paediatrics of the UZ Brussel and consists of several research clusters. Historically, the group has been interested in metabolic diseases such as lysosomal storage diseases and this has led to the close collaboration with the neuro-paediatricians of the hospital, investigating mitochondrial ...