Projects
Immune master-switches in spondyloarthritis. KU Leuven
Role of mechanical strain in spondyloarthritis: a proof of concept study Ghent University
The abstract for "Role of mechanical strain in spondyloarthritis: a proof of concept study" is missing. Please contact the promotor for more information.
Towards a better understanding of functioning in patients with axial spondyloarthritis: an application of the International Classification of Functioning, Disability and Health (ICF) model KU Leuven
The concept of Spondyloarthropathy (SpA) embodies a family of rheumaticdiseases characterized by inflammation and damage in the form of destruction and/or bone formation at the synovio-entheseal complex. In axial SpA, disease processes typically occur in the vicinity of the sacroiliac joints and result in the feeling of stiffness, the loss of mobility and inflammatory back pain. Recently, the Assessment of SpondyloArthritis international ...
Fund for scientific research on Rheumatology: "PRIOR-M: Predicting treatment Response In spOndyloarthRitis using gut Microbiome" Ghent University
Fund for scientific research on Rheumatology: "Artificial intelligence for early detection of spondyloarthritis in medical imaging: development and validation of novel CT and MRI use cases for clinical practice" Ghent University
Deciphering the functional phenotype of ?d T cells in spondyloarthritis. Ghent University
Spondyloarthritis (SpA) is a chronic immune-mediated inflammatory disease affecting not only the joints and entheses, but also barrier tissues: gastrointestinal tract, skin and the eye. γδ T cells, a population of innate-like T lymphocytes, play a crucial role in the SpA pathology. In this project, we aim to investigate the functional phenotype γδ T cells in SpA through the prism of unresolved, clinically-relevant questions. It is not clear ...
Deciphering the functional phenotype of γδ T cells in spondyloarthritis. Ghent University
Accumulating evidence points towards the crucial role of γδ T lymphocytes in the pathogenesis of spondyloarthritis (SpA). The project aims to elucidate their exact influence in disease development and different organ involvement. This truly translational project combines cutting-edge analysis of the multilevel regulation of immune cell function in unique patient samples with innovative research on mouse model of SpA.
Further deepening of the market potential of new biomarkers for the diagnosis of axial spondyloarthritis Hasselt University
Show us what you can: final validation of instrumented assessments of functioning in patients with axial spondyloarthritis. KU Leuven
The assessment of functioning is considered kay in the management of axial spondyloarthritis. A final validation of these instruments is urgently needed to improve daily care.