(Pre-)Clinical investigation of the role of mechanosensors in skeletal muscle mass homeostasis and maintenance KU Leuven
Skeletal muscle tissue permits essential vital function (e.g. respiration, circulation or locomotion) and controls metabolism. Dysfunction and specifically loss of skeletal muscle mass accelerate diseases, e.g. cancer or critical illness. This accentuates the relevance of skeletal muscle mass maintenance. However, the understanding of mechanisms that control skeletal muscle mass is highly fragmentary and its improvement will lay the ...