IPAFLU: A prospective study assessing the incidence of invasive pulmonary aspergillosis (IPA) and identifying host and microbial risk factors predisposing to IPA among critically ill patients with severe influenza KU Leuven
Each year, influenza causes ~30,000 U.S. deaths, the majority of which stem from influenza pneumonia or secondary bacterial or fungal pneumonia. Aspergillus fumigatus is the leading cause of post-influenza fungal pneumonia. A retrospective study of ICU patients with influenza in Europe showed that 14% of patients without typical risks for invasive fungal infection developed invasive pulmonary aspergillosis (IPA). The mortality rate of IPA ...