Projects
Use of frontline technologies to screen pathogens, environment and pigs for a better disease control in swine herds Ghent University
The pig industry has evolved extremely fast during the last decades. The exponential increase in the number of animals combined with their worldwide transport and the globalization of feed components favors a continuous fast spread of infectious agents throughout the world. Major gaps in their control are difficulties to (1) recognize diseases at an early stage, (2) swiftly identify pathogens and pathogen complexes, and (3) convince farmers ...
The Authoring Side Revisited: Tracking Writing and Reading Processes in Technical Communication KU Leuven
The Authoring Side Revisited: Tracking Writing and Reading Processes in Multimodal Technical Communication KU Leuven
EV-TRACE: Extracellular Vesicle Tracking using surface proteins and Resonance Assays to detect breast Cancer in Early stage Ghent University
Extracellular Vesicle Tracking using surface proteins and Resonance Assays to detect breast Cancer in Early stage (EV-TRACE) A major challenge in cancer is to detect the disease early on and it locate organ of origin while stratifying patients to receive appropriate treatment to increase survival and quality of life. Most cancers that are detected early can only be cured by surgery; so without any systemic therapy. New, inexpensive and ...
Extracellular Vesicle Tracking using surface proteins and Resonance Assays to detect breast Cancer in Early stage (EV-TRACE) KU Leuven
Problem
Early detection reduces cancer-related deaths because time is a matter of life and death for a cancer victim. Diagnostic screening tests must be sensitive, specific, inexpensive, non-invasive and provide sufficient lead-time. Single markers typically lack sensitivity and specificity. Extracellular Vesicles (EV) in liquid biopsies hold promise in the non-invasive detection of cancer because their molecular content (proteins, ...
Autonomous light tracking system containing well-developed photocatalysts for enhanced nitrate reduction to ammonia generation KU Leuven
Nitrate reduction to ammonia (NRA) is a very recent yet effective strategy to convert NO3- into NH3 at ambient conditions. It is a promising alternative for the Haber-Bosch process and as such an important step to realizing a fully carbon-neutral Europe. By employing density functional theory calculations, the first aim of this project is to screen different NRA catalysts (e.g., transition metal compounds), investigate the relationship ...
Development and in vivo validation of a kit for polyamine transport tracking and quantification KU Leuven
Tracking changes in the histone modification pattern by untargeted mass spectrometry Ghent University
This dissertation describes both the biological and technical aspects of one specific epigenetic template: histones and their modifications.
In this dissertation, we profile the histone epigenome of human embryonic stem cells (hESCs) during conversion from the primed to the naive state using an untargeted mass spectrometry (MS)-based approach. In total, 23 histone post-translational modifications (hPTMs) changed significantly over ...
Efficiency and ex post screening in higher education - a dynamic discrete choice approach. KU Leuven
Many students drop out of secondary or higher education without obtaining a degree. A recent policy report (OECD, 2012) illustrates the problems: 16% of today's young adults in OECD countries do not complete secondary education. Up to 62% enter a university-level program, but only 39% are expected to complete it. Among the students who complete a degree, there is a large fraction that incurs substantial delays.
In this thesis, we ...