Development of a scale–up method for single phase liquid and multiphase solid–liquid batch processes based on in situ measurement of heat mixing KU Leuven
Non-continuous batch reactors are of crucial importance for industries like the pharmaceutical, fine chemistry, food, pulp and paper industry and biotechnology due to their versatility and flexibility. During scale-up, the scale of the batch process increases from lab to industrial scale. Scale-up problems can occur due to changes in heat or mass transfer. This research develops a new scale-up method that uses heat mixing in order to avoid ...