Drug response profiling of T-cell acute lymphoblastic leukemia to optimize salvage therapeutic strategies for refractory/relapsed patients Ghent University
T-cell acute lymphoblastic leukemia (T-ALL) is a rare aggressive hematological malignancy that is
characterized by the diffuse infiltration of the bone marrow by malignant T-cell progenitors. Due to the
introduction of intensified combination chemotherapy, the prognosis of T-ALL has significantly improved
over the last years, with current protocols reaching cure rates over 80% in children and about 50% in
adults. Nonetheless, the ...