3D-RET: unlocking 3D genome architecture in human retina using C-technologies Ghent University
Human adult neural retina contains seven major cell classes and is bordered by the retinal pigment epithelium (RPE) and choroid layer. Cis-regulatory elements (CREs) in human adult and developing retina have been mapped using bulk and single-cell transcriptomics and epigenomics, providing insight into gene regulation and contributing to non-coding variant interpretation in inherited retinal diseases (IRD). IRD represent a major cause of ...