Publications
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A multiscale hybrid model for exploring the effect of Resolvin D1 on macrophage polarization during acute inflammation Hasselt University
Dysregulated inflammation underlies various diseases. Specialized pro-resolving mediators (SPMs) like Resolvin D1 (RvD1) have been shown to resolve inflammation and halt disease progression. Macrophages, key immune cells that drive inflammation, respond to the presence of RvD1 by polarizing to an anti-inflammatory type (M2). However, RvD1's mechanisms, roles, and utility are not fully understood. This paper introduces a gene-regulatory network ...
Resolving some spatial resolution issues : part 2 : when diffraction takes over Ghent University
In part 1 “Between line pairs and sampling distances” of this split entry on spatial resolution, it was mentioned that this second part would focus on some fundamental laws of electromagnetic radiation to shed more light on the concepts of spatial resolving power and spatial resolution. The numbering of chapters, illustrations and equations simply continues so that one can easily merge both parts into one larger text. However, and in contrast to ...
Resolving some spatial resolution issues : part 1 : between line pairs and sampling distance Ghent University
Optimization of elution conditions and comparison of emerging biocompatible columns on the resolving power and detection sensitivity of oligonucleotides by ion-pairing reversed-phase liquid chromatography mass spectrometry Vrije Universiteit Brussel
A generic performance comparison strategy has been developed to evaluate the impact of mobile-phase additives
(ion-pairing agent / counter ion systems), distinct stationary phases on resulting resolving power, and MS
detectability of oligonucleotides and their critical impurities in gradient IP-RPLC. Stationary-phase considerations included particle type (core-shell vs. fully porous particles), particle diameter, and pore size. ...
(ion-pairing agent / counter ion systems), distinct stationary phases on resulting resolving power, and MS
detectability of oligonucleotides and their critical impurities in gradient IP-RPLC. Stationary-phase considerations included particle type (core-shell vs. fully porous particles), particle diameter, and pore size. ...
Selectivity and Resolving Power of Hydrophobic Interaction Chromatography Targeting the Separation of Monoclonal Antibody Variants Vrije Universiteit Brussel
This study presents a comprehensive investigation of the mechanistic understanding of retention and selectivity in hydrophobic interaction chromatography. It provides valuable insights into crucial method-development parameters involved in achieving chromatographic resolution for profiling molecular variants of trastuzumab. Retention characteristics have been assessed for three column chemistries, i.e., butyl, alkylamide, and long-stranded ...