LXRbeta, a janus-face in de- and remyelination Hasselt University
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that affects young adults in the prime of their life. There is a urgent need for improved therapies that halt disease progression and boost repair. MS is thought to be initiated by autoreactive T cells that instruct phagocytes to degrade the insulating myelin sheath around nerves (demyelination). Myelin has an high cholesterol content. Our recent findings show ...