Projects
Regucyte : Bringing Regenerative Medicine to the Clinic Ghent University
Adipose tissue and its byproducts are often used in the operating room (OR). Adipose tissue is transplanted in the same patient to treat surgical defects. Byproducts such as stromal vascular fraction (SVF) are used in regenerative medicine. When working with adipose tissue, an ischemia time of less than 6h is respected. Afterwards adipose tissue and its byproducts suffer cell death. We discovered a new technology to prolong the survival of ...
Uncoupling beneficial from deleterious outcomes derived from Wnt/beta-catenin activation in stem cells for new strategies in anticancer therapy and regenerative medicine. KU Leuven
Mechanical Tissue Loading for Musculoskeletal Regenerative Medicine KU Leuven
Several research groups within KU Leuven focus on understanding the homeostasis, degeneration and adaptation of musculoskeletal tissue in order to improve its regeneration. Tissue studied range from cartilage and bone, over ligaments and tendons, to muscles. There is therefore an imminent need for a dedicated set-up that allows the controlled application of complex loading conditions to tissues in long-term in vitro culture. Such a set-up is ...
NanoCT and bioreactor CT for a better understanding of the dynamics of 3D tissue formation in regenerative medicine KU Leuven
As cell clusters, tissues and organs are 3D structures with a complex spatial heterogeneity, traditional 2D imaging techniques such as histology are insufficient to investigate the dynamics of tissue remodeling taking place during development, pathology, regeneration and repair. To provide more accurate and spatiotemporal quantitative 3D information on these dynamic biological processes, the consortium will purchase a nanofocus X-ray computed ...
Advanced Materials for Regenerative Medicine and Medical Devices in contact with the human body. Ghent University
MATMED aims to effect major positive impacts on health and wellbeing in the North-West Europe region by breaking down the barriers that prevent product innovations from reaching both patients and the wider population. The programme supports SMEs working in the fields of Advanced Materials, Medical Devices and Regenerative Medicine, enables high-quality transnational collaborations, and accelerates commercialisation in these medical areas.
Driving endothelial cell specification in pluripotent stem cells and identifying organ(oid) specific vascularization for regenerative medicine KU Leuven
The vascular endothelium is essential to maintain vascular tone in health but is central to the aberrant function of both large and small blood vessels in vascular disease. Within each organ, the endothelium is highly heterogenous. Studying vascularization principles within organs and organoids are important for understanding organ-specific functions of the vasculature and defining new strategies for regenerative medicine. The proposed aims ...