PEA histone modification proteomics Ghent University
Olink's groundbreaking proteomics panels help scientists discover human protein biomarkers. Proximity Extension Assay (PEA) technology measures up to 1463 unique proteins in 88 samples simultaneously, starting from less than 3 microliters from nearly any type of biological sample. Unique application domains are located where mass spectrometry (MS) based proteomics is suboptimal. Samples such as cerebrospinal fluid (CSF), microdialysis ...
Special Research Fund Professorship in proteomics Ghent University
Automated sample preparation for mass spectrometry-based proteomics using the DigestPro MSi instrument. Ghent University
Mass spectrometers are essential instruments for contemporary proteome analysis. Typically, proteins are digested into peptides prior to analysis. In our labs this crucial step is not automated, implying that variation is inevitably introduced by manual intervention. Here, by installing a robot for fully automated sample preparation we will increase the overall quality of our proteome research.
Using molecular signaling profile in white blood cells measured by highly-sensitive mass spectrometry (MS)-based proteomics in the differential diagnosis between major depressive disorder and bipolar disorder. University of Antwerp
Proteomics Expertise Center Ugent Ghent University
The Proteomics Expertise center groups expertise in (quantitative analysis) of proteins, their post-translational modifications en their interactions using mass spectrometry technology. It shares it facilities with researchers who need proteomics for functional research on proteins in the broad application field of Life Sciences (biomedical, food, environment)
Mining the Musa biodiversity for drought tolerance: allele discovery via integrated phenomics, proteomics and transcriptomics KU Leuven
Banana (Musa spp.) is one of the most produced fruits in the world, the production exceeded 122 million tons in 2013. For optimal production the crop requires: 1200–2690 mm water/year, depending on the agro-ecological zone. The limited genetic diversity in commercial plantations renders the crop extremely vulnerable for (a)biotic stress, like drought. However, worldwide a huge (uncharacterized) biodiversity is available, and we ...
In depth insight into the translatome using state-of-the-art proteomics and ribosome profiling, applications on different in vitro model systems. Ghent University
From a proteogenomic approach, bioinformatic tools will be developped to combine ribosome profiling and mass spectrometry results. These tools will secure exhaustive analysis of different translation features and controls. Experiments will be performed in cell lines and afterwards in embryoid and organoid bodies, as a proxy to in vivo tissue.
Applying proteomics and metabolomics for studying human trapezius myalgia and the effect of dry needling Ghent University
The first aim is to gain better insight in the pathophysiological processes of trapezius myalgia using a combination of microdialysis samples AND muscle biopsies in 25 patients with trapezius myalgia and 25 healthy subjects. The second aim is to more understand the effects of dry needling. Both acute and long term effects will be evaluated using a similar measurement protocol.