Projects
The cystic fibrosis lung in the era of modulator therapy: a longitudinal study of the lung bacterial and fungal microbiome and improving personalized phage therapy to treat multi-drug resistant infections Ghent University
Background and objectives
Modulator therapy in cystic fibrosis (CF) has led to a substantial clinical improvement of the CF patient population. However, there is currently lack of data and no consensus regarding the long-term impact of modulators on the lung microbiome and infections. Studies are often limited by the lack microbiological resolution, focus on single pathogens and none studied the Belgian CF population. Importantly, no ...
HavePhAIth: Human Phage therapy using AI to design phage cocktails against ESKAPE pathogens KU Leuven
Phage for flavour: Phage therapy to eradicate off-flavour producing bacteria from recirculating aquaculture systems KU Leuven
A digital phagogram for personalized phage therapy Ghent University
Pathogenic bacteria increasingly become resistant to antibiotics, leading to a decreasing number of therapeutic options, with even no options in case of pandrug-resistant strains. The increasing number of untreatable bacterial infections has sparked a renewed interest in phage therapy in the Western world. Phage therapy is the therapeutic use of phages (viruses that infect bacterial cells) against bacterial infections. Belgium has recently ...
Implementation of Personalized PHAGE therapy to combat difficult-to-treat infections (IP-PHAGE) KU Leuven
HavePhAIth: Human phage therapy against the ESKAPE pathogens using AI KU Leuven
Human Phage Therapy (PT) is a promising route for the treatment of drug-resistant bacterial infections. Belgium is currently leading the implementation of PT in Europe, and the technique is currently in operations at the Queen Astrid Military Hospital (QAMH) and at UZ Leuven. A Multidisciplinary Phage Task Force (MPTF) has been set up within UZ Leuven to provide a PT framework for patients with difficult-to-treat infections. However, the ...
Phage therapy for improving sludge quality: towards healthier and more energy-efficient water treatment HOGENT
Optimalization of phage therapy against bacterial pathogens in cabbage and leek Inagro vzw
Optimization of phage therapy against bacterial pathogens in cabbage and leek KU Leuven
In the recent LO-Project IWT.100881 promising results were obtained with phage therapy. The ultimate goal of this process is to translate these results into a strategy for the control of bacterial pathogens in cabbage and leek.