Projects
Mechanistic insight in peroxidase activity towards industrial applications. University of Antwerp
Boosting stress resilience of Arabidopsis by heterologous expression of a selenocysteine containing glutathione peroxidase Flanders Institute for Biotechnology
Unraveling the intimate structure-function relation in chlorite dismutases and dye-decolorizing peroxidases using electron paramagnetic resonance. University of Antwerp
Phenol oxidases and peroxidases in the enzyme pools of the heathland soils and effects of the climate change on the activities of these soil enzymes Hasselt University
PhotoChromic HYdrogen PERoxide biosensors for super-resolution imaging of hydrogen peroxide microenvironments KU Leuven
In cells, hydrogen peroxide (H2O2) is deliberately produced and is key for a healthy cellular metabolism, and an adequate H2O2 production and delivery is required for correct cellular and tissue functions. The majority of this H2O2 production occurs in cellular microdomains, and the signalling actions in these microdomains are restricted to a very confined area. Most of these discoveries were made possible thanks to the use of ...
Molecular mechanisms underlying peroxisome-mediated changes in the cellular hydrogen peroxide signaling network KU Leuven
For a long time, hydrogen peroxide (H2O2) was considered as a detrimental by-product of oxidative metabolism. However, during the last decades, this molecule has moved into the forefront as a central second messenger in many biological processes, mainly through reaction with cysteine thiolate groups that can be found in specific protein microenvironments. An important site of cellular H2O2 metabolism are peroxisomes. However, their role in ...
Electrochemical synthesis of hydrogen peroxide from water and oxygen KU Leuven
The presence of organic contaminants in wastewater poses considerable risks to the health of both humans and ecosystems. Hydrogen peroxide (H2O2) is an important chemical commodity that has been widely used as an environmentally benign oxidant and a potential energy carrier in various applications, including wastewater treatment, disinfection, chemical synthesis, paper/pulp bleaching, semi-conductor cleaning, and fuel cells. My work is arm to ...
Green Synthesis of Hydrogen Peroxide from alternative sources Using innovative Photocatalysts. University of Antwerp
Molecular targets and mechanisms involved in peroxisomal hydrogen peroxide signaling KU Leuven
Peroxisomes are indispensable organelles that are best known for their role in cellular lipid and hydrogen peroxide metabolism. Hydrogen peroxide is an important signaling messenger that controls many cellular processes by modulating protein activity through cysteine oxidation. Somewhat surprisingly, the potential involvement of peroxisomes in hydrogen peroxide-mediated signaling processes has been overlooked for a long time, and – at ...