Perianal fistulas in Crohn’s disease: new insights on pathogenesis, diagnosis and treatment. KU Leuven
Introduction Perianal fistulizing Crohn’s disease (pCD) develops in 20% and recurs in 30% of Crohn’s disease (CD) patients and typically follows a relapsing and remitting course. (1) The natural course of the disease is highly unpredictable. Most data are derived from outdated population-based studies and historical series. (2-5) After a mean duration of 10 years, 51% of patients with pCD are in stable remission, 9% have persistent drainage ...