Endometrial cancer organoids as a novel in vitro model to decipher pathogenesis and identify new drug targets KU Leuven
Endometrial cancer (EC) is the most common gynecological malignancy in industrial countries, and its incidence is steadily increasing. Despite large efforts to understand the pathogenesis of EC (and its different subtypes), underlying mechanisms remain largely unknown, and therapy efficiency and overall survival rate of advanced stages has not substantially improved in the last decade, mainly due to the lack of reliable study models. Here, we ...