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Palliative sedation in a specialized unit for acute palliative care in cancer hospital: comparing patients dying with and without palliative sedation. Vrije Universiteit Brussel
Palliative sedation is undergoing extensive debate. The aims of this study were to describe the
practice of palliative sedation at a specialized acute palliative care unit and to study whether
patients who received palliative sedation differed from patients who did not. We performed
a systematic retrospective analysis of the medical and nursing records of all 157 cancer
patients who died at the acute palliative care unit ...
practice of palliative sedation at a specialized acute palliative care unit and to study whether
patients who received palliative sedation differed from patients who did not. We performed
a systematic retrospective analysis of the medical and nursing records of all 157 cancer
patients who died at the acute palliative care unit ...
Tumor Response and Symptom Palliation from RAINBOW, a Phase III Trial of Ramucirumab Plus Paclitaxel in Previously Treated Advanced Gastric Cancer KU Leuven
BACKGROUND: In the intent-to-treat (ITT) population of the RAINBOW study, objective response rate (ORR) was 28% and 16% in the ramucirumab and control arms, respectively. To further characterize tumor response, we present details on timing and extent of tumor shrinkage, as well as associations with symptom palliation. MATERIALS AND METHODS: Tumor response was assessed with RECIST v1.1, and quality of life (QoL) was assessed with the European ...
Lumen-apposing metal stent through the meshes of duodenal metal stents for palliation of malignant jaundice Vrije Universiteit Brussel
Background and study aims Endoscopic retrograde cholangiopancreatography (ERCP) is the gold standard procedure for malignant jaundice palliation; however, it can be challenging when a duodenal self-expandable metal stent (SEMS) is already in place. Patients and methods The primary aim of our study was to evaluate the technical feasibility of the placement of a lumen apposing metal stent (LAMS) through the mesh (TTM) of duodenal stents. The ...
No advantage of expanded polytetrafluoroethylene and fluorinated ethylene propylene-covered stents over uncovered nitinol stents for percutaneous palliation of malignant infrahilar biliary obstruction : results of a single-center prospective randomized tr Ghent University
Purpose: To prove that covered stents are more efficacious than uncovered stents regarding patency, safety, enabling of chemotherapy, and survival in percutaneous palliation of malignant infrahilar biliary obstruction. Materials and Methods: After failed endoscopic treatment, 154 patients with obstructive jaundice caused by unresectable infrahilar malignancy were randomly allocated to receive an expanded polytetrafluoroethylene and fluorinated ...
Outcome of the Glenn procedure as definitive palliation in single ventricle patients University of Antwerp KU Leuven
Objectives: In selected single ventricle patients, a Glenn procedure (SV-Glenn) may be considered as definitive palliation. Either the patient is unsuited to progress to a Fontan circulation or a SV-Glenn circulation is preferred. This study aimed at describing the clinical course, and long-term mortality/morbidity of SV-Glenn patients. Methods: All SV-Glenn patients followed at the University Hospitals Leuven before May 2018 were included. ...
Percutaneous obliteration of the right ventricle to avoid coronary damage by sinusoids in patients with pulmonary atresia intact ventricular septum during staged single ventricle palliation KU Leuven
BACKGROUND AND AIMS: Suprasystemic pressure waves can damage the coronary arteries resulting in myocardial ischemia and excess early mortality. We aimed to reduce the coronary pressure wave through the sinusoids by abolishing RV volume with percutaneous devices. METHODS AND RESULTS: Four patients with PA-IVS and coronary sinusoids from the hypertensive rudimentary RV were evaluated at a median age 26.6 months (range: 2.7-51.7). Right ventricle ...
Cost Efficacy of Metal Stents for Palliation of Extrahepatic Bile Duct Obstruction in a Randomized Controlled Trial KU Leuven
BACKGROUND & AIMS: Endoscopic stents are placed for palliation of extrahepatic bile duct obstruction. Although self-expandable metal stents (SEMS) remain patent longer than plastic stents, they are more expensive. We aimed to evaluate which type of stent (plastic, uncovered SEMS [uSEMS], or partially covered SEMS [pcSEMS]) is the most effective and we assessed costs. METHODS: We performed a multicenter randomized trial in 219 patients at 18 ...
Pulmonary Artery Banding as "Open End" Palliation of Systemic Right Ventricles: An Interim Analysis KU Leuven
OBJECTIVES: A morphological right ventricle (RV) is not ideally suited for the long-term maintenance of the systemic circulation. The aim of this analysis was to evaluate the intermediate results and outcome of pulmonary artery banding (PAB) in an open-ended strategy. METHODS: This is a retrospective review of patients with systemic RVs who had undergone PAB in our institution from April 1985 to January 2011. PAB was placed in 5 patients late ...