Synthetic organogenesis: using in vivo cellular reprogramming to induce ectopic organs KU Leuven
Our long-term goal is to find ways to induce synthetic organogenesis, that is to produce miniorgans that function in vivo. With the term "miniorgan" we mean multicellular assemblies that i) contain all major cell types normally present in an organ, ii) that show morphological organization within the miniorgan, and iii) that functionally integrate into the host tissue. Thus, miniorgans may be smaller than regular organs, but they are fully ...