Understanding how neutrophil extracellular traps (NETs) contribute to vulnerability of the ageing heart KU Leuven
Ageing is a major risk factor for heart failure, which is a leading cause of mortality worldwide. Which factors and processes render the elderly heart more vulnerable to additional stressors, like hypertension, remains unclear. Growing evidence suggests that the hearts’ resident cells (cardiomyocytes and fibroblasts) are not the sole contributors to this increasing vulnerability. With ageing, the immune system undergoes a shift from adaptive ...