Neuronal Wiring Lab (VIB-KUÂ Leuven) KU Leuven
Dietmar Schmucker and his team study the neuronal interactions and the neuronal network of the model organisms Drosophila and Xenopus tropicalis.
Dietmar Schmucker and his team study the neuronal interactions and the neuronal network of the model organisms Drosophila and Xenopus tropicalis.
The research interests of the Laboratory of Neuronal Communication are defined as:
Altered synaptic communication has been identified as one of the leading causes of various neurological and psychiatric disorders, yet the underlying molecular mechanisms remain unresolved. Hence, establishing an understanding of synaptic communication at the molecular level in relation to neurological disease, in particular Parkinson’s disease, would be ...
The Laboratory of Neuronal Differentiation conducts research into four research lines:
The ‘Neuro-Aging’ team focuses on glutamate transport, with emphasis on system xc - , in health and disease. We have ongoing projects on the role of system xc - or the cystine/glutamate antiporter in e.g. Parkinson’s disease, Alzheimer’s disease, and (central effects of) (pancreatic) cancer. In most of these projects, neuroimmune communication is receiving increasing attention. Our overall hypothesis that inhibition of system xc - might be a ...
The Laboratory of Ion Channel Research. main interest is the mammalian TRP channel family, a class of structurally related non selective cation channels, some of which mediate Ca2+-entry in response to activation of phospholipase C (PLC) . Others act as cellular sensors that translate fluctuations in environmental parameters, such as thermal (heat, cold), mechanical (touch) and chemical (tastants) stimuli, into changes in membrane ...