Projects
Establishing neuroimmune brain organoids as a platform for neurodegenerative and neurodevelopmental disease research. University of Antwerp
Towards an integrative model of spoken and written word processing in the intact brain and its decline in primary progressive aphasia and neurodegenerative disease KU Leuven
Characterization of the impact of proteins linked to neurodegenerative diseases in the yeast Saccharomyces cerevisiae KU Leuven
Our society will have to face an estimated of about 65 million cases of dementia in 2030 and 115 million cases by the year 2050. Alzheimer's Disease represents the majority of these cases. Despite tremendous efforts of the research community to unravel the disease mechanisms, there is still a lack of insight in disease pathogenesis. This disorder is substantially heterogeneous, both at the level of genetics as well as at the level of clinical ...
Building towards a patent - Exploitation of the killifish R&D platform to combat neurodegenerative diseases KU Leuven
Design and developement of diagnostics and drugs for neurodegenerative, immunological and microbial diseases KU Leuven
The research aims at two important goals:
1) The development of (fluorescent) tools to visualize biomarkers in neurodegenerative diseases as research tools or diagnostics
In this part of the work fluorescent molecules are developed and optimized. Key goals are to increase the biocompatibility, stability, specificity and (to later enable in vivo imaging applications) a suitably red-shifted fluorescence. Key biomarkers of ...