Cell-cell cOmmuNicaTion As a driver of Cancer cell state identiTy - Decoding the impact of cell-cell communications on the identity of tumor states in skin cancers Ghent University
Different tumor states (TS) exist within a given tumor with some cancer cells actively dividing, while others differentiate, invade the surrounding tissues, give rise to metastasis, or are in a dormant and therapy-resilient state. The identification of the intrinsic and extrinsic mechanisms that modulate TS diversity is essential for the development of new therapeutic strategies. In this project, we will dissect the mechanisms by which ...