Projects
Deciphering the network that links nutrient signaling in yeast with growth potential, pH and Ca2+ homeostasis, ageing and lifespan, resistance and virulence. KU Leuven
Cells of all living organisms are equipped with complex signal transduction networks enabling to make appropriate changes in metabolism in response to environmental changes. In this project, our focus is on how several signaling pathways in brewer’s yeast and pathogenic fungi integrate to control traits like stress resistance, reserve carbohydrate metabolism, lipid metabolism, ageing and lifespan, drug tolerance and, in case of pathogenic ...
Multinational firms in (Global) Cities: Mimicry, Knowledge networks, and Economic Growth KU Leuven
This dissertation examines the dynamic interrelationship between MNEs and cities. First, it examines cities as MNEs’ foreign direct investment location choice and imitation processes within these FDI location choices. Imitation not only enhances the attractiveness of the city by contributing to the generation of agglomeration economies and by encouraging additional imitation, but it also contributes to the further development of the ...
Identification of the molecular networks involved in leaf growth through a systems biology approach Ghent University
Plant growth and the influence of the environment on this growth are important aspects of plant physiology. Despite the fundamental importance of plant growth little is known on the molecular networks that govern size and growth rate of organs such as leaves. This project aims to unravel the regulatory pathways that drive leaf growth in a systems biology approach.
Leaf growth - from genes to networks Ghent University
The aim of this project is to understand the molecular networks governing biomass production in higher plants. Arabidopsis and Brachypodium lines that produce more biomass under either optimal or drough stress conditions will be compared phenotypically and molecularly. Genes that enhance plant growth will be combined.
Evolving views on the worlds languages in a globalizing world (1540-1840): information growth, conceptual shifts, scholarly networks in the circulation of linguistic knowledge. KU Leuven
Yeast Bioreactor: Network biology of stress responses and cell flocculation of Saccharomyces cerevisiae grown in a continuous bioreactor in microgravity conditions Ghent University
The global project objective is the development of a dynamic proteomics platform and its use on-orbit for three specific microgravity research topics based on eukaryotic cell types: the yeasts Saccharomyces cerevisiae and Candida albicans, and human osteoblast cells. The platform is based on a microfluidic cellular microarray system. The miniturisation by using microfluidics is necessary to perform on-orbit systems biology. With this ...
Yeast Bioreactor 2020: Network biology of stress responses and cell flocculation of Saccharomyces cerevisiae grown in a continious bioreactor in microgravity conditions Ghent University
Yeast cultivations will be performed in a specifically designed continuous bioreactor. An integrative-experimental approach will be used to assess the effect of microgravity. Therefore, various omics technologies, i.e. fluxomics, transcriptomics, proteomics and genomics, and specific cell analysis methods will be used to analyse the samples. A network biology model for S. cerevisiae will be set-up to process the omics data. This will lead to ...
Yeast Bioreactor 2019: Network biology of stress responses and cell flocculation of Saccharomyces cerevisiae grown in a continious bioreactor in microgravity conditions Ghent University
Yeast cultivations will be performed in a specifically designed continuous bioreactor. An integrative-experimental approach will be used to assess the effect of microgravity. Therefore, various omics technologies, i.e. fluxomics, transcriptomics, proteomics and genomics, and specific cell analysis methods will be used to analyse the samples. A network biology model for S. cerevisiae will be set-up to process the omics data. This will lead to ...
Yeast Bioreactor 2018: Network biology of stress responses and cell function of Saccharomyces cerevisiae grown in a continuous bioreactor in microgravity conditions Ghent University
In this project, the behaviour of yeast (adhesion, metabolims) is investigated in microgravity. This research used facilities of the International Space Station ISS