Projects
Feeling, thinking, acting: Pathways to parenting in parents of children with profound intellectual and multiple disabilities KU Leuven
The study of precursors and factors associated with joint attention behaviours in people with profound intellectual and multiple disabilities. KU Leuven
Towards robust disability prediction in multiple sclerosis from brain MRI. University of Antwerp
Identifying novel insights into molecular pathways that contribute to axonal loss in progressive multiple sclerosis. KU Leuven
Multiple sclerosis (MS) cannot be cured and with >11 classes of disease-modifying treatments, one of the biggest challenges in therapeutic decision-making is effective stratification of treatment in the face of an uncertain prognosis. Indeed, it is not clear why certain individuals with MS go on to develop significant disabilities, in terms of walking or cognition, while others don't. One of the biggest challenges for clinicians is ...
Inflammasome activation in TH lymphocytes, induced by mitochondrial impairment, causes local tissue damage in the brain of multiple sclerosis patients. Hasselt University
New kids on the block: Improving the care of people with multiple sclerosis by introducing "RADIOMICS" and "EPOMICS". Hasselt University
Beyond multiple sclerosis susceptibility: disentangling heterogeneity of disease. KU Leuven
Multiple sclerosis (MS) is one of the most common neurological disorders in young adults, affecting around 10,000 people in Belgium and 2.5 million worldwide. The disease can lead to important physical as well as cognitive disability at a time that is crucial in the personal and professional development of patients. MS is characterized by three hallmarks: inflammation, demyelination or destruction of the protective myelin sheath surrounding ...
Somatic mutations explain missing risk of multiple sclerosis. KU Leuven
Somatic mutations explain missing risk in multiple sclerosis
An Goris, Laboratory for Neuroimmunology, KU Leuven
1. State of the art
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, affecting 2.5 million
people worldwide and leading to important physical and cognitive disability with typical onset during
young adulthood. A genetic component has long been demonstrated and through ...