deCIPHER: COMPREHENSIVE CHEMICAL PROFILING AND BIOPHYSICAL CHARACTERIZATION OF EMERGING BIOPHARMACEUTICALS USING NATIVE MULTI-DIMENSIONAL LIQUID CHROMATOGRAPHY Vrije Universiteit Brussel
chromatography (MD-LC) platform to i) separate high complex
mixtures of monoclonal antibody (mAb) variants with unparalleled
resolving power, and ii) assess biophysical characteristics of the
individual variants. In WP#1, high-resolution MD-LC workflows with
native stationary-phase modulation will be developed for
comprehensive chemical profiling of ...