Laboratory for Experimental Mouse Genetics KU Leuven
The research of the Laboratory for Experimental Mouse Genetics is focused upon the study of the function of the multifunctional cell surface receptor, lipoprotein receptor-related protein 1 (LRP1). Via a novel application of recombinase-mediated cassette exchange (RMCE) multiple knock-in mutation were generated in this receptor, especially in the intracellular domain of this receptor, effecting the interaction of the receptor with ...