Projects
'Molecular Imaging' meets 'Imaging Molecules' University of Antwerp
SRP-Onderzoekszwaartepunt: ITAREG: Molecular Imaging and TArgeting of immunoREGulatory cells in Inflammatory diseases and cancer Vrije Universiteit Brussel
Molecular Imaging Center Antwerp - Bio-Imaging Lab (MICA-BIL). University of Antwerp
Cardiac remodeling after acute myocardial injury – understanding functional,cellular and molecular mechanisms by longitudinal in vivo imaging to reveal mechanisms for restoring endogenous cardioprotection. KU Leuven
Method development for multi-modal imaging mass spectrometry (LA-ICP-MS and MALDI-MS): fusing elemental with molecular information to gain insight into hypoxia-driven processes in cancer Ghent University
Tumor hypoxia is one of the hallmarks of cancer and has turned into a central issue in cancer treatment since it is associated with malignant tumor progression, resistance to therapy and increased metastatic spread. To date, many aspects of hypoxia-induced changes in tumors remain to be elucidated. This drives the need to develop multi-modal imaging workflows for discovering and identifying key biomolecules in the heterogeneous tumor ...
The synthesis of novel CXCR4 antagonists for use in oncology and molecular imaging KU Leuven
Protein aggregation and folding as target for molecular imaging and radionuclide therapy KU Leuven
Design and development of a new vector platform for CXCR4-targeted molecular imaging and radionuclide therapy KU Leuven
The CXC chemokine receptor 4 (CXCR4) is a well-described G protein-coupled receptor (GCPR) that is involved in different physio-pathological processes upon binding of its endogenous ligand CXC chemokine 12 (CXCL12). CXCR4 is expressed throughout development and adulthood on a variety of cell types including lymphocytes, endothelial, epithelial and hematopoietic stem cells (HSCs). CXCR4 plays a fundamental physiological role in hematopoiesis, ...