Therapeutic manipulation of the gut microbiome in inflammatory bowel disease KU Leuven
Crohn’s disease (CD) and ulcerative colitis (UC) are idiopathic inflammatory bowel diseases (IBD) characterized by chronic relapsing inflammation of the gut. The peak onset of both diseases is during adolescence and young adulthood. The incidence of IBD is rising worldwide. The conventional treatment options (5-aminosalicylates, thiopurines, methotrexate and/or biological agents as anti-TNF antibodies or vedolizumab) aiming at suppressing the ...