Study of β-lactam induced bacteriolysis using high-throughput time-resolved microscopy and mechanical bacteriolysis by nanostructured surfaces KU Leuven
Bacteriolysis is one of the most widely used modes of killing bacteria. β-lactam antibiotics, antimicrobial peptides, glycopeptides, phage therapy and nanostructured antibacterial surfaces kill bacteria principally by inducing lysis. A deeper understanding of the process of bacteriolysis can inspire new ways to prevent bacterial colonization and increase antibiotic efficacy.
In the first part of this work, we develop a high-throughput ...