Antimalarial treatment efficacy and safety in pregnant women Institute of Tropical Medicine
Specific Objectives:
1. To characterise the malaria endemicity in Nchelenge district;
2. To determine the ...
TUDCA-ALS will focus on amyotrophic lateral sclerosis (ALS) a rare neurodegenerative disorder, that affects motor neurons in the brain, brainstem and spinal cord, resulting in progressive weakness and atrophy of voluntary skeletal muscles. ALS has an estimated prevalence of 5.40 cases per 100.000 population corresponding at about 40.000 patients at European level. Treatments are modestly effective at best, and the majority of patients die ...
Thanks to worldwide research nanotechnology is one of the key drivers of the current scientific advancements in the 21st century. The field has expanded astonishingly over the last decade, where it is estimated that nearly 10 % of all publications indexed in Web of Science in 2016 involved nanotechnology. Nonetheless, despite this extensive research the translation of these widely investigated nanoparticles (NPs) toward the clinic is rather ...
The main objective of this research hypothesis-driven proposal is to investigate whether latent or chronic non-lethal viral infections interfere with the efficacy of RNAi in insects. Up until now, the impact of such viruses on the RNAi response in insects has not been investigated. The project will make use of multiple biotechnology and insect physiology technologies to realize 5 specific objectives. In brief: deep sequencing technology will ...
Our aim is to develop within the EU region an original research activity programme with technical applications to the design of new solid state pharmaceuticals, with a view to facilitating the development of both new and existing drugs in forms with improved bioavailability, efficacy, chemical and physical stability, safety and predictability. The new forms will mainly be based on nanoparticle technologies, amorphous drug forms and molecular ...
This project studies the bio-analysis and toxicokinetics of endotoxins and eicosanoids in broiler chickens.