Characterization and therapeutic potential of chemokine action in sepsis and flavivirus-induced encephalitis KU Leuven
Inflammation assists in the defense against viral and bacterial infections, but needs to be tightly controlled. Indeed, an insufficient immunological response may fail to clear pathogens from the body, while overactivation or inappropriate downregulation of inflammation may lead to permanent tissue damage. Chemokines are crucial players in inflammatory reactions and are regulated by transcription and translation of chemokine ligands and ...