The role of the epiplayer RBBP4 in malignant progression and relapse in multiple myeloma. Vrije Universiteit Brussel
located in the bone marrow. MM remains incurable, as most patients
in remission develop a tumor that is resistant to all drugs. Epigenetic
defects play a major role in MM, by promoting aggressiveness, drug
resistance and disease progression. Targeting the enzymes
responsible for these epigenetic changes (the epiplayers) holds
promise to ...