Combination of targeted therapy and chemotherapy in acute lymphoblastic leukemia KU Leuven
Acute lymphoblastic leukemia (ALL) is an aggressive leukemia that is most common in children and adolescents. Long-term ALL survival rates have significantly improved by the use of intensified chemotherapy and reach 80% in pediatric cases, and 60% in adult ALL, but are associated with substantial acute and long-term side effects. Research from the past 10 years has identified several new targets for therapy in ALL, which can be targeted by ...