Understanding how fatty liver disease reprograms liver cancer cells KU Leuven
Liver cancer is a deadly disease and its occurrence is growing worldwide. Notably, the rise in obesity caused by modern western diet (high fat, high sugar, high cholesterol) is correlated with an increased cancer incidence and mortality. Western diet causes chronic fatty liver disease that progresses to nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and eventually liver cancer. However, how fatty liver disease promotes tumor ...