Projects
Does temperature determine the variation in bacterial membrane lipids (brGDGTs) and community composition along an altitudinal gradient in subarctic soils? University of Antwerp
Role of endoplasmic reticulum (ER) stress induced immunogenic lipids in cancer immunotherapy Ghent University
The unfolded protein response is a conserved signalling pathway which aims to maintain cellular
homeostasis under conditions which promote endoplasmic reticulum (ER) stress. Both protein and
lipid biosynthesis are hallmark responses of the UPR whereas failure to restore cellular
homeostasis during UPR is widely acknowledged to promote inflammation and tumorigenesis. A
specialized subset of T cells ...
Oxidative and lipolytic stability of lipids in autotrophic microalgal biomass during storage and drying. KU Leuven
Autotrophic microalgae are unicellular aquatic organisms that immobilize CO2 from atmosphere and produce oxygen by photosynthesis. Microalgae contain a relatively high amount of lipids and are consequently a promising alternative source of biodiesel. The lipids from several microalgae contain also nutritionally interesting omega-3 long-chain polyunsaturated fatty acids, which makes them interesting for several food and other high value ...
Charting the biosynthetic landscape of a novel class of bioactive specialized lipids KU Leuven
Microorganisms produce a wealth of specialized metabolites with highly diverse chemical structures and important applications in medicine and agriculture. The zeamines are an unusual group of longchain polyamine antibiotics produced by Serratia bacteria that exhibit potent activity against a broad spectrum of (micro)organisms, including bacteria, fungi, plants and nematodes. They are assembled by a unprecedented combination of polyketide, ...
Aliterations in membrane lipids as an adaptice response to high intratumoral pressure: a novel ubiqutous therapeutic target KU Leuven
Approximation properties for groups lie at the intersection of functional analysis and geometric group theory, which are central areas in modern mathematics. Such properties often act as bridges between these two fields. Probably, the most well-known approximation property is amenability, which was introduced in 1929 by von Neumann in his work on the Banach-Tarski paradox and has been a key ingredient in several groundbreaking results since. ...
Icelandic Soils, Lipids and Microbiomes: towards a better understood climate proxy. University of Antwerp
Design of hierarchical bifunctional zeolite catalysts for the deoxygenation of lipids. KU Leuven
The role of the interaction of the PDZ protein syntenin 2 with nuclear lipids and nucleic acids. KU Leuven
PDZ (</>PSD-95/Discs-large/ZO-1</>)</> </>d</>omains are </>key components of scaffold proteins acting as hubs controlling the specificity, dynamics and flow of cellular information. </>The original view envisioned PDZ domains as protein-protein interactions domains </>supporting</> the </>assembly </>of </>multi</>protein complexes at the membrane. ...
Resolving Alzheimer’s Disease: the role of immunoresolvent lipids in the microglia response to amyloid plaques KU Leuven
Microglia are the immune cells of the brain. In healthy conditions, these immune cells surveil their surroundings to support and protect brain cells from hazardous insults. Upon injury or disease, microglia produce an inflammatory response aimed at restraining the damage and restoring the normal function of the brain. However, this inflammatory response must be properly controlled and resolved, since a failure in the resolution of ...