Projects
LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapy Ghent University
Macrophages are increasingly recognized as key regulators of common
diseases such as neurodegeneration, cancer and liver disease. Central to
macrophage functionality is their ability to attain different activation
states, ranging from inflammation-inducing to inflammation-resolving
and healing states. The precise phenotype and functions adopted are
highly context dependent and have been shown ...
LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapy Hasselt University
LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapy KU Leuven
Macrophages are increasingly recognized as key regulators of common diseases such as neurodegeneration, cancer and liver disease. Central to
macrophage functionality is their ability to attain different activation states, ranging from inflammation-inducing to inflammation-resolving
and healing states. The precise phenotype and functions adopted are highly context dependent and have been shown to be driven by the local ...
SBO Project : LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapy Vrije Universiteit Brussel
diseases such as neurodegeneration, cancer and liver disease. Central to
macrophage functionality is their ability to attain different activation
states, ranging from inflammation-inducing to inflammation-resolving
and healing states. The precise phenotype and functions adopted are
highly context dependent and have been shown to be driven by ...
The role of lipidomics in early postoperative Crohn’s recurrence. KU Leuven
The general aim of this PhD project is to identify triggers of post-operative recurrence in Crohn’s disease (CD), by focusing both on the external and the luminal side of the intestine. We specifically want to characterize the lipidomic landscape of creeping fat in CD, and if these signatures can predict post-operative recurrence. We further want to define the luminal components contributing to post-operative recurrent CD and link these to ...
Lipometrix – towards an integrated lipidomics platform. KU Leuven
Lipometrix is a recently established KU Leuven Core Facility specializing in lipidomics. This emerging analytical discipline relies on mass spectrometry for the measurement of thousands of lipid species from diverse samples, including cell culture, blood and tissue. As such, the development of techniques for sample preparation, automation, measurement protocols, and complex data analysis and interpretation are core areas of research. This ...
Challenges in mass spectrometry: computational lipidomics and MS imaging Hasselt University
LipoScan: a mass spectrometry-based lipidomics platform for cancer diagnostics and target identification KU Leuven
The use of metabonomics and lipidomics in the discovery of new actionable vulnerabilities in BRAF-mutated melanoma KU Leuven
De doelstelling van dit thesisproject is de impact te bestuderen van de lipogene transcriptiefactor SREBP-1 op het cellulaire metabolisme via nucleaire magnetische resonantie. De uiteindelijke betrachting is deze bevindingen te vertalen naar nieuwe disgnostische merkers en doelwiiten voor therapie in het domein van kanker en neurodegeneratieve aandoeningen.