Projects
Compensation funds: their nature, function and legality University of Antwerp
The Power of the Congregation for the Doctrine of the Faith to Derogate from Prescription: an Evaluation of the Legality and Justice of the 2002 Rescript KU Leuven
This dissertation evaluates the legality and justice of the 2002 rescript authorizing the Congregation for the Doctrine of the Faith “to derogate from the terms of prescription on a case-by-case basis.”
Chapter two investigates the juridic foundations of the institute of extinctive prescription and provides an historical overview of its raison d’être. The results suggest that the positive law right not to be accused of a crime ...
Normative reform through experimentalist implementation processes:tracing the impact of stakeholder involvement in redefining timber legality KU Leuven
This research aims to generate insights about the normative and practical merits of experimentalist governance (EG) processes in practice, in particular in view of accommodating local contestation and deliberation at the implementation stage. By discussing the effects of opening up the regulatory process at the country-level, we wish to look into how experimentalist problem-solving practices can encourage a more democratic and inclusive ...
Spatial-omics deciphering of cellular and molecular responses to enhanced MYCN/ATR-CHK1 synthetic lethality in high-risk neuroblastoma Ghent University
Neuroblastoma (NB) is a devastating childhood cancer with poor prognosis and limited options for novel precision therapies. Our teams (Ghent-Gothenburg) independently discovered the strong therapeutic potential of targeting DNA damage signaling (ATR-CHK1) by showing the value of sensitization of ATR/CHK1 drugging through combination with inhibition of enzyme component RRM2 implicated in DNA replication. In addition, durable responses were ...
The locality of transnational solidarity within the European Union (LOTSEU) Ghent University
This research project investigates local support for European Union (EU) wide solidarity policies among the citizenry. It combines earlier approaches taken in the field of European solidarity research with those of cleavage theory and political geography to shed light over the impact of small-scale contextual factors on public preferences towards an EU-wide social layer. To pursue this scientific endeavor I will, firstly, exploit a natural ...
Reconciliation of quantum non-locality with relativistic locality KU Leuven
Quantum theory and relativity theory are two pillars of modern day
theoretical physics. Quantum theory gives the description of
microscopic systems, while relativity theory mainly deals with the
large-scale structure of space-time. However, there is a tension
between these theories. On the one hand, relativity theory is a theory
in which locality holds: this means that there are no faster than light
influences. ...
Scrutinizing selective Aurora Kinase A inhibition as a novel entry point for synthetic lethality in neuroblastoma Ghent University
Neuroblastoma is the most common extra-cranial solid tumor in children. Currently, despite multi-modal therapy, survival rates remain disappointingly low and survivors often suffer from major long-term effects of intensive therapy. Aurora kinase A (AURKA) has previously been identified as a potential drug target in high-risk neuroblastoma. However, despite the promising preclinical data for first generation inhibitors including alisertib, ...
The Depths of the Megacity. Recent Literary Imaginaries of the Underground in Mexico City KU Leuven
This project proposes to make a fundamental contribution to contemporary literary and urban studies by focusing on the literary representation of Mexico City’s underground spaces. In spite of its remarkable presence in recent Latin American literature, this topic is completely new as a scholarly subject. In narrative texts that take place in Mexico City, subterranean spaces (metro, tunnels, sewers, etc.) frequently appear and imply a ...